摘要 |
PURPOSE:To provide the method for efficiently producing an epsilon-poly-L-lysine, enabling the semi-continuous production or continuous production of the epsilon-poly-L- lysine without lysing the cells of a bacterium by employing the immobilized cells of the bacterium. CONSTITUTION:Immobilized cells produced by immobilizing the genus Streptomyces organism having an epsilon-poly-L-lysine-producing ability are used under an aerobic condition for the production of the epsilon-poly-L-lysine, and the produced epsilon-poly-L-lysine is recovered. The epsilon-poly-L-lysine-producing bacterium can repeatedly be used, and the bacterial cells are readily removed and recovered, thereby permitting to economically supply the epsilon-poly-L-lysine. |