发明名称 PLASMA CHOLESTEROL DEPRESSANT AND ITS PRODUCTION
摘要 PURPOSE:To provide the subject depressant containing, as active ingredient, a polysaccharide found in tea leaves. CONSTITUTION:The objective plasma cholesterol depressant containing, as active ingredient, a polysaccharide obtained by extracting tea leaves with water or warm water. This polysaccharide (M-15) can be obtained by a process wherein tea leaves are extracted with water or warm water followed by eliminating the ingredients of about >=200000 in molecular weight using a polysulfone-based ultrafiltration membrane and then further eliminating the ingredients of about <=20000 in molecular weight using another polysulfone-based filtration membrane; the remaining fraction is injected into a column packed with a styrene- divinylbenzene-based polymer, and ethanol is added to the resulting discharged solution followed by being left at rest for about a whole day and night at a low temperature, and the resulting precipitate is subjected to high-performance liquid chromatography to separate the target polysaccharide (M-15). This depressant is useful as a preventive/medicine for hyperlipemia as an inducive factor for diseases such as obesity, arteriosclerosis, and thrombosis.
申请公布号 JPH0680580(A) 申请公布日期 1994.03.22
申请号 JP19920258965 申请日期 1992.09.02
申请人 ITOUEN:KK 发明人 TAKEO CHUICHI;KAWASAKI TOSHIO
分类号 A61K31/715;A61K36/18;A61P3/06 主分类号 A61K31/715
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