摘要 |
PURPOSE:To provide a liposome having excellent stability, reticuloendothelial avoidance, organotropic property, drugretaining function, etc. CONSTITUTION:The objective liposome can be prepared by compounding (i) a polar lipid, (ii) a compound giving positive or negative charge, (iii) cholesterol, (iv) a compound containing a polyethylene glycol unit having a polymerization degree of 3-6 and at least two 5-20C alkyl groups (or its lipid derivative), (v) a drug component and (vi) a solvent at specific ratios. |