发明名称 Guanidine compounds
摘要 A compound of formula (I): <IMAGE> (I) in which: R1 represents substituted or unsubstituted phenyl or (C3-C7) cycloalkyl, R2 represents trifluoromethyl or (C3-C4) cycloalkyl, A represents -CH2-, -CH=N-, =N- or -NH-, R3 and R4, which may be identical or different, represent hydrogen or linear or branched (C1-C6) alkyl or, with the nitrogen atoms to which they are attached, form a 5- or 6-membered heterocycle, R represents either hydrogen in the case where A=-CH2-, -CH=N- or -NH-, or a bond of the group A when the latter is equal to =N-, its enantiomers and epimers as well as its addition salts with a pharmaceutically acceptable acid.
申请公布号 US5296498(A) 申请公布日期 1994.03.22
申请号 US19930005653 申请日期 1993.01.19
申请人 ADIR ET COMPAGNIE 发明人 MALEN, CHARLES;LACOSTE, JEAN-MICHEL;DE NANTEUIL, GUILLAUME
分类号 A61K31/155;A61K31/415;A61K31/495;A61P3/04;A61P3/08;A61P3/10;A61P9/00;A61P9/12;A61P11/00;A61P25/24;A61P25/26;C07C279/06;C07C279/08;C07C281/16;C07C281/18;C07D233/48;C07D233/50;C07D233/52;C07D239/14;C07D239/18;(IPC1-7):A61K31/415 主分类号 A61K31/155
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