NEW HIV-1 ISOLATES OF A SUBTYPE AND ITS DIFFERENTIAL DIAGNOSIS, VACCINE AGAINST HIV-1 INFECTION OF THIS SUBTYPE AND PROCESS FOR PREPARING AND USING THE HIV-1 ISOLATE

摘要

Three new HIV-1 isolates HIV-1D747 (ECACC V92082718), HIV-1D757 (ECACC V92082719) and HIV-1D760 (ECACC V92082720) are disclosed, which represent a further indenpendent subtype of the HIV-1 family and have been recovered from Indian patients which at the time when the virus was isolated showed no typical AIDS symptoms. Also disclosed are vaccines against HIV-1 infections by this subtype and a process for producing the same, as well as the use of the HIV-1 isolates to produce protective vaccines against HIV-1 infections and for therapeutical use after HIV-1 infection, as well as for differential diagnosis.