发明名称 PHENYLNAPHTHALENE LACTONES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS
摘要 Compounds having formula (I) are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.
申请公布号 CA2143221(A1) 申请公布日期 1994.03.17
申请号 CA19932143221 申请日期 1993.08.19
申请人 MERCK FROSST CANADA INC 发明人 GIRARD YVES;HAMEL PIERRE
分类号 A61K45/06;C07D405/14;C07D493/08;(IPC1-7):C07D405/14;C07H7/04;C07D407/14;C07D409/14;C07D413/14;C07D417/14;A61K31/44;A61K31/495;A61K31/70 主分类号 A61K45/06
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