| 发明名称 |
ANTIHYPERCHOLESTEROLEMIC COMPOUNDS AND RELATED PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE |
| 摘要 |
Novel antihypercholesterolemic agents are provided. An exemplary group of compounds has the structural formula (I) <IMAGE> (I) wherein R is a C-17 side chain, R1 is -OH, =O, or the like, and X and Y are CH, C-OH, C-OCH3 or C-Z. Methods of using the compound of formula (I) or other novel oxysterol analogs to treat hypercholesterolemia are provided, as are pharmaceutical compositions containing the compounds. |
| 申请公布号 |
WO9325568(A3) |
申请公布日期 |
1994.03.17 |
| 申请号 |
WO1993US05580 |
申请日期 |
1993.06.10 |
| 申请人 |
SRI INTERNATIONAL |
发明人 |
CHONG, WESLEY, K., M.;CHAO, WAN-RU;YASUDA, DENNIS, M.;JOHANSSON, JOHN, G.;AVERY, MITCHELL, A.;TANABE, MASATO |
| 分类号 |
A61K31/58;A61K31/567;A61K31/575;A61P3/00;A61P3/06;A61P9/10;C07D261/20;C07J3/00;C07J7/00;C07J9/00;C07J31/00;C07J53/00;C07J71/00;(IPC1-7):C07J1/00 |
主分类号 |
A61K31/58 |
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