发明名称 |
Monoklonalt antistoff til anvendelse in vitro for diagnose av maligne tumor- eller akutte inflammasjonssykdommer, og som er spesifikt for N-acetyl-neuraminsyre i hybridom som produserer antistoffet |
摘要 |
A hybridoma producing a monoclonal antibody specific to N-acetylneuraminic acid or a derivative thereof in the beta-arrangement as an epitope or antigenic determinant is herein disclosed. The monoclonal antibody produced by the hybridoma can be used in clinical purposes such as diagnosis and/or prognosis of a certain kinds of cancers and acute inflammatory diseases. The hybridoma can be generated by fusing (i) B cells or lymphocytes obtained by immunizing an animal with an N-acetylneuraminic acid or a derivative thereof in beta-arrangement as an antigen and (ii) myeloma cells. |
申请公布号 |
NO174110(C) |
申请公布日期 |
1994.03.16 |
申请号 |
NO19880005053 |
申请日期 |
1988.11.11 |
申请人 |
MECT CORPORATION |
发明人 |
KAWAMURA, ATSUSHI;SUDA, ISAO;TAKADA, KINJI;ITO, MASAYOSHI;SHITORI, YOSHIYASU |
分类号 |
G01N33/53;A61K38/00;A61K39/395;C07K16/18;C07K16/30;C12N5/18;C12N5/20;C12P21/08;C12R1/91;G01N33/574 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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