| 摘要 |
PCT No. PCT/JP88/00276 Sec. 371 Date Sep. 15, 1989 Sec. 102(e) Date Sep. 15, 1989 PCT Filed Mar. 17, 1988 PCT Pub. No. WO88/06898 PCT Pub. Date Sep. 22, 1988.A membrane type oxygenator for effecting exchange of gases with a porous gas-exchange membrane possessing minute through pores forming a path for gas, which membrane type oxygenator is characterized by the fact that minute particles are retained in the minute pores of the porous gas-exchange membrane to permit a decrease in the cross-sectional area of the path for gas and as blood anticoagulant is retained in the minute particles or between the minute particles, and it is manufactured assembling a membrane type oxygenator containing a porous gas-exchange membrane possessing minute through pores forming a path for gas, then causing a dispersion of minute particles to flow through the interior of the membrane type oxygenator thereby allowing the minute pores to retain the minute particles and permitting a decrease in the cross-sectional area of the path for gas, removing the dispersion remaining within the membrane type oxygenator, and further causing a liquid containing a blood anticoagulant to flow through the interior of the oxygenator and allowing the liquid to pass through the minute pores of the gas-exchange membrane thereby inducing deposition of the blood anticoagulant on the minute particles.
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