发明名称 |
A novel b-lymphoma cell line and antigen |
摘要 |
<p>This invention provides an IL-6 dependent B-cell lymphoma cell line designated DS-1 deposited with the American Type Culture Collection, wherein the cell line is reactive with a monoclonal antibody produced by a hybridoma cell line designated 10D2F6 deposited with the American Type Culture Collection. The invention also provides a purified antigen reactive with a monoclonal antibody produced by 10D2F6. The antigen also exists on DS-1. Also provided is a method of detecting the presence of an antigen-stimulated T-cell comprising detecting the presence of the antigen on a lymphocyte. In addition, the invention provides a method of detecting the presence of a neoplastic cell comprising detecting the presence of the antigen on a cell which is not normal a T-cell.</p> |
申请公布号 |
AU5084493(A) |
申请公布日期 |
1994.03.15 |
申请号 |
AU19930050844 |
申请日期 |
1993.08.20 |
申请人 |
US ARMY |
发明人 |
BOCK GLENN H;NELSON DAVID L;KURMAN CAROLE C;FLEISHER THOMAS A |
分类号 |
G01N33/53;A61K38/00;C07K14/725;C07K16/28;C07K16/30;C12N5/09;C12N5/10;C12N15/09;C12P21/02;C12P21/08;G01N33/577;(IPC1-7):C12N5/08;A61K39/395;G01N33/574;G01N33/68;C12N15/12;C07K15/00;C07K17/00 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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