| 摘要 |
5-Trifluoromethyluracil is obtained by chlorinating thymine under mile conditions, further chlorinating the 2,4-dichloro-5-methylpyrimidine obtainable in this way under drastic conditions to give 2,4-dichloro-5-trichloromethylpyrimidine, reacting the latter with a fluorinating agent to give 2,4-fluorinated and/or chlorinated 5-trifluoromethylpyrimidines and subjecting these to a hydrolysis. In the course of this process, the novel chemical compounds 2,4-dichloro-5-trichloromethylpyrimidine and 2,4-difluoro-5-trifluoromethylpyrimidine are obtained. |
