摘要 |
There are provided substituted acetamide derivatives represented by general formula (I): (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, n and Z are defined in the specification. The substituted acetamide derivatives strongly inhibit acylcoenzyme A cholesterol acyltransferase (ACTA) and are expected to be effective for the treatment and prevention of hypercholesterolemia, hyperlipemia and arteriosclerosis.
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申请人 |
BANYU PHARMACEUTICAL CO., LTD. |
发明人 |
IWASAWA, YOSHIKAZU;HATTORI, HIROMI;NAGATA, YASUFUMI;SHIMIZU, AKIKO;SAWASAKI, YOSHIO |