| 发明名称 |
Monoclonal antibodies to CMP-170 antigen on activated endothelial cells. |
| 摘要 |
<p>Monoclonal antibodies are produced that bind specifically to CMP-170 antigen present in the cytoplasm of resting and IL-1 activated endothelial cells and on the surface of IL-1 activated endothelial cells. The monoclonal antibodies and antigens are useful in the preparation of a medicament for treating inflammatory responses associated with activated endothelial cells and for diagnosing inflammatory response.</p> |
| 申请公布号 |
EP0585963(A1) |
申请公布日期 |
1994.03.09 |
| 申请号 |
EP19930116072 |
申请日期 |
1990.05.21 |
| 申请人 |
OTSUKA PHARMACEUTICAL CO., LTD. |
发明人 |
NEWMAN, WALTER;WILSON, DIANE O.;GOPAL, VENCAT T. |
| 分类号 |
G01N33/53;A61K38/00;A61K39/00;A61K39/395;A61P9/00;A61P11/16;A61P29/00;A61P37/06;C07K14/435;C07K14/705;C07K16/00;C07K16/28;C12N15/12;C12P21/00;C12P21/06;C12P21/08;C12R1/91;G01N33/571;(IPC1-7):C12P21/08;G01N33/577 |
主分类号 |
G01N33/53 |
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