发明名称 |
Method of preparing medical aerosol formulations including drug dissolved in reverse micelles |
摘要 |
The present invention provides a method for the production of medicinal aerosol compositions which are made up of a homogenous solution of aerosol propellants, a surfactant and a pharmaceutically active compound, where the process comprises purifying the surfactant, removing the water from the surfactant, and dispersing the surfactant in an aerosol propellant with a hydrophilic pharmaceutical composition and a controlled amount of water. The present invention also provides medicinal aerosol compositions produced by this method which are a homogenous solution of the pharmaceutically active compound contained in reverse micelles made up of the surfactant; and methods of using the medicinal aerosols to provide an effective amount of a therapeutic agent.
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申请公布号 |
US5292499(A) |
申请公布日期 |
1994.03.08 |
申请号 |
US19920828195 |
申请日期 |
1992.01.30 |
申请人 |
UNIVERSITY OF WALES COLLEGE OF CARDIFF |
发明人 |
EVANS, RICHARD M.;FARR, STEPHEN J. |
分类号 |
A61K9/00;A61K9/107;A61K38/28;(IPC1-7):A61K9/12 |
主分类号 |
A61K9/00 |
代理机构 |
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地址 |
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