| 摘要 |
Imidazolidyl macrolides of the general structural Formula I: <CHEM> have been prepared from suitable precursors by alkylation and/or arylation at C-3= and/or C-4= of the cyclohexyl ring. These macrolide immunosuppressants are useful in a mammalian host for the treatment of autoimmune diseases, infectious diseases the prevention of rejection of foreign organ transplants and/or related afflictions, diseases and illnesses. |
