| 摘要 |
PURPOSE: To measure a biological fluid with high sensitivity by providing a porous matrix of fiber and solid particles, wherein the particles have a substance reacting on an analyte in a sample to the surface thereof and held fixedly in the matrix. CONSTITUTION: A material for an analytical unit 10 comprises a porous fiber matrix. The fibrous material has a mean diameter of about 0.1-10μm and has a plurality of spherical solid particles, being held fixedly on the fiber. The negative control region 30 of the matrix 12 does not contain a substance holding an enzyme label, and a signal reactive material within a control region 32 is provided with a substance to be bonded with an enzyme label and other signal reactive materials. In an analyte bonding region 32, microparticles in an area 34 of the matrix 12 is coated with a substance, e.g. an antigen or antibody, to be bonded with the analyte. Positive test results obtained through the correct use of the unit 10 causes '+' reaction both in the control region 32 and the analyte bonding region 34, while negative test results causes '-'reaction in the control region 32, thus providing valid test results. When the reagent does not function correctly, no reaction takes place in the control region 32 or the analyte bonding region 34, and invalid test results are provided.
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