| 摘要 |
PCT No. PCT/GB90/01021 Sec. 371 Date Mar. 14, 1991 Sec. 102(e) Date Mar. 14, 1991 PCT Filed Jul. 2, 1990 PCT Pub. No. WO91/00351 PCT Pub. Date Jan. 10, 1991.A polypeptide sequence from Candida albicans is described which has significant sequence homology with known stress proteins from other organisms, particularly the heat shock protein hsp 90 of Sacchromyces cerevisiae. Corresponding DNA sequences are also described, together with antibodies raised against fragments of the sequence. The polypeptide and DNA sequences and antibodies provide separate means for the diagnosis and/or treatment of fungal, particularly Candida, infections.
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