| 发明名称 |
MELANIN FORMATION-INHIBITORY PROTEIN, AND ITS PREPARATION AND USES |
| 摘要 |
A novel melanin formation-inhibitory protein, which has a molecular weight of 90,000?20,000 and a pI of 5.5?0.5, exerts a tyrosinase formation-inhibitory activity in pigment cells but does not substantially inhibit the inherent tyrosinase activity. Thus the protein is advantageously used as a pharmaceutical and cosmetic in the prevention and/or treatment for local chromatosises such as chloasma, ephelis and sunburn, as well as systemic chromatosises such as addisonism.
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| 申请公布号 |
CA2104043(A1) |
申请公布日期 |
1994.02.22 |
| 申请号 |
CA19932104043 |
申请日期 |
1993.08.13 |
| 申请人 |
KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO |
发明人 |
FUKUDA, SHIGEHARU;SUEMOTO, YASUO;KURIMOTO, MASASHI |
| 分类号 |
A61K8/72;A61K8/00;A61K8/64;A61K8/98;A61Q17/04;A61Q19/00;A61Q19/02;C07K14/435;C07K14/47;C12P21/00;C12R1/91;(IPC1-7):C12P21/00;A61K7/02;A61K38/17 |
主分类号 |
A61K8/72 |
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