| 发明名称 |
INHIBITOR RESISTANT SERINE PROTEASES |
| 摘要 |
Serine proteases of the chymotrypsin superfamily are modified so that they exhibit resistance to serine protease inhibitors. If such modified serine proteases have fibrinolytic, thrombolytic, antithrombotic or prothrombotic properties, they are useful in the treatment of blood clotting diseases or conditions. |
| 申请公布号 |
WO9403614(A1) |
申请公布日期 |
1994.02.17 |
| 申请号 |
WO1993GB01632 |
申请日期 |
1993.08.03 |
| 申请人 |
BRITISH BIO-TECHNOLOGY LIMITED |
发明人 |
DAWSON, KEITH, MARTYN;GILBERT, RICHARD, JAMES |
| 分类号 |
C12N15/00;A61K38/00;A61K38/43;A61K38/46;A61P7/02;C07H21/04;C12N1/21;C12N5/10;C12N9/64;C12N9/68;C12N9/72;C12N9/74;C12N9/76;C12N15/09;C12N15/55;C12N15/57;C12R1/19;C12R1/865;(IPC1-7):C12N15/57;C12N15/58;C12N1/19;C12N15/15;C12N9/66;A61K37/547 |
主分类号 |
C12N15/00 |
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