| 摘要 |
<p>Disclosed is a stopper for use with containers to provide needleless access to the container with a cannula having a blunt penetrating tip. Also disclosed is a system comprising the stopper, container and cannula. The stopper includes a disc (29) having an upper face (31) and a lower face (33), and a plug (27) extending from the disc into the container. Also included is a diaphragm (37), defined by a target region in the upper face and a cross channel (41) in the disc for controlling the force needed to penetrate the stopper with the cannula. The plug includes a first inward surface (43) for guiding the cannula and a second inward suface (45) for engaging the cannula to minimize wetting of the outside of the cannula. In a preferred embodiment, the first surface (43) extends down from the cross channel (41) on the lower side of the disc, radially outwardly to a maximum diameter and the second inwardly facing surface (45) extends down from the first surface radially inwardly to a minimum diameter to form the cannula seal. Also shown is a centrally located piercing point positioned to pre-slit the diaphragm. An overcap may be provided to alternatively have an axially aligned boss and bore positioned to pre-slit the diaphragm. In another embodiment, the invention includes an annular pre-slit disc (59) formed of self sealing material and positioned to reduce spray back when inserting or removing the cannula.</p> |
