发明名称 2-HETEROCYCLIC-5-HYDROXY-1,3-PYRIMIDINES USEFUL AS ANTIINFLAMMATORY AGENTS
摘要 The present invention is novel compounds which are 2-heterocyclic-4,6-ditertiarybutyl-5-hydroxy-1,3-pyrimidines, where heterocyclic is selected from imidazole, thiazole, and oxazole, and pharmaceutically acceptable additional salts, bases, and base salts thereof, pharmaceutical compositions and methods of use therefor. The invention compounds are found to have activity as inhibitors of 5-lipoxygenase and/or cyclooxygenase providing treatment of, for example, preferably inflammation.
申请公布号 WO9403448(A1) 申请公布日期 1994.02.17
申请号 WO1993US07034 申请日期 1993.07.27
申请人 WARNER-LAMBERT COMPANY 发明人 CONNOR, DAVID, THOMAS;KOSTLAN, CATHERINE, ROSE;UNANGST, PAUL, CHARLES
分类号 A61K31/505;A61K31/506;A61P29/00;A61P37/08;A61P43/00;C07D403/04;C07D413/04;C07D417/04;(IPC1-7):C07D403/04 主分类号 A61K31/505
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