N-sulfonyl-tetrahydro-[1,3]-dioxepino[5,6-biazirines, intermediates for their preparation and their use

摘要

Starting from cis-2-butene-1,4-diol, via the 4,7-dihydro-1,3-dioxepin and trans-6-acylamino-5-chloro-1,3-dioxepans the novel tetrahydro-(1,3)-dioxepino(5,6-b)-azirines were synthesized, and therefrom the novel hypoglycaemically active N-sulfonyl-tetrahydro-(1,3)-dioxepino(5,6-b)azirines. The inventive compounds are valuable intermediates in the synthesis of other, biologically active substances.