| 摘要 |
PURPOSE:To provide the new compound sufficiently keeping various bioactivities of laminin as a cell-adhesive protein, exhibiting a cancer metastasis inhibitory effect higher than in a known laminin core sequence, ready to synthesize and free from a serious side effect on the human body. CONSTITUTION:A peptide of the formula, its pharmaceutically permissible salt and a cancer metastasis inhibitor containing the same compound. R-X-Tyr-Ile- Gly-Ser-Arg-Y. (R is hydrogen atom or a 2 to 4C acyl group; X is Glu or Asp residue; Y is NR<1>R<2>. R<1> and R<2> are each hydrogen atom or a 1 to 4C alkyl group. Both R<1> and R<2> may be same or different, provided that both of these are not hydrogen atom). |
