| 发明名称 |
Oligonucleotide alkylphosphonothioates |
| 摘要 |
The invention provides improved oligonucleotides having greater resistance to nucleolytic degradation by virtue of having alkylphosphonothioate or arylphosphonothioate internucleotide linkages. |
| 申请公布号 |
AU4688393(A) |
申请公布日期 |
1994.02.14 |
| 申请号 |
AU19930046883 |
申请日期 |
1993.07.26 |
| 申请人 |
HYBRIDON INC |
发明人 |
PADMAPRIYA A;AGRAWAL SUDHIR |
| 分类号 |
C12N15/09;A61K31/70;A61K31/7088;A61K48/00;A61P31/04;A61P31/12;A61P35/00;C07H21/00;C07H21/04 |
主分类号 |
C12N15/09 |
| 代理机构 |
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代理人 |
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| 主权项 |
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