| 发明名称 |
PREPARATION OF 3-HYDROXY-5-OXO, 3-OXO-5-HYDROXY AND 3, 5-DIHYDROXYESTER BY STERICALLY SELECTIVELY MICROBIAL OR ENZYMATIC REDUCTION OF 3, 5-DIOXO- ESTER |
| 摘要 |
Microorganisms or reductases derived therefrom reduce a diketo ester <CHEM> to form the associated 3-hydroxy, 5-hydroxy, or 3,5-dihydroxy esters. Selected microorganisms produce the preferred stereoisomers <CHEM> which can be used to prepare antihypercholesterolemic agents such as <CHEM> |
| 申请公布号 |
JPH0630783(A) |
申请公布日期 |
1994.02.08 |
| 申请号 |
JP19930112778 |
申请日期 |
1993.05.14 |
| 申请人 |
BRISTOL MYERS SQUIBB CO |
发明人 |
RAMESHIYU ENU PATERU;KURAIDO JII MAKUNAMII;AMITSUTO BANAAJII;RAZURO JIEI SHIYARUKA |
| 分类号 |
C07D319/06;C07D405/06;C12P7/62;C12P17/16;C12R1/01;C12R1/365;C12R1/645;C12R1/78;C12R1/84;C12R1/865;(IPC1-7):C12P7/62 |
主分类号 |
C07D319/06 |
| 代理机构 |
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| 地址 |
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