发明名称 |
RECOMBINANT ADENOVIRUS VACCINES |
摘要 |
This invention provides a method of producing antibodies or cell mediated immunity to an infectious organism in a warm blooded mammal which comprises administering to said warm blooded mammal intranasally, intramuscularly, or subcutaneously, live recombinant adenoviruses in which the virion structural protein is unchanged from that in the native adenovirus from which the recombinant adenovirus is produced, and which contain the gene coding for the antigen corresponding to said antibodies or inducing said cell mediated immunity.
|
申请公布号 |
CA2101463(A1) |
申请公布日期 |
1994.02.08 |
申请号 |
CA19932101463 |
申请日期 |
1993.07.28 |
申请人 |
AMERICAN HOME PRODUCTS CORPORATION |
发明人 |
DAVIS, ALAN R.;HUNG, PAUL P.;LUBECK, MICHAEL D.;NATUK, ROBERT J.;CHANDA, PRANAB K.;MURTHY, SHRIDHARA C. S.;LEE, SHAW-GUANG L. |
分类号 |
A61K39/235;A61K39/00;A61K39/21;A61P31/12;A61P31/18;C07K14/16;C12N7/00;C12N7/01;C12N15/861;C12P21/00;C12R1/92;(IPC1-7):C12N7/01;A61K39/12;A61K39/295;A61K39/42;C12N15/86 |
主分类号 |
A61K39/235 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|