| 摘要 |
<p>The present invention provides a method of inducing immunity to retroviral infection in a human or other mammal comprising administration of a preparation comprising retroviral antigen in an amount effective to induce a cell mediated immune response substantially free of a humoral immune response. There is also provided a vaccine effective against HIV. In one aspect, the immunogen is useful for immunizing an individual previously infected by a retrovirus including HIV, so as to induce immunoprotective factors protective against progression of the infection. In another aspect, the vaccine is useful for vaccinating an individual not previously infected with HIV in order to prevent subsequently acquired infection. In another aspect, there is provided a method of rendering a viral immunogen non-infectious.</p> |
