RECOMBINANT ANTIBODY AGAINST HUMAN INTERLEUKIN-1

摘要

A chimeric antibody against human IL-1, and other human-mouse chimeric and reshaped antibodies, wherein the L chain has the constant region of human antibody molecules and the variable region of mouse antihuman IL-1 antibody molecules having the amino acid sequence described in the sequence identification no. 1 and the H chain has the constant region of human antibody molecules and the variable region of mouse antihuman IL-1 antibody molecules having the amino acid sequence described in the sequence identification no. 2. This antibody is utilizable in treating various diseases accompanied by the abnormal production of IL-1 and conducting diagnostic imaging of IL-1 producing sites in the body.