CLINICAL TEST FOR DETECTION OF ALZHEIMER'S DISEASE

摘要

A clinical method for the detection of Alzheimer's disease in living patients tests cerebrospinal fluid obtained from the patient. The cerebrospinal fluid is tested using a Western blot analysis to determine reactivity with a polyclonal or a monoclonal antibody. The antibody is one which reacts with a broad band of immunoreactivity obtained upon separation of Alzheimer's specific, material derived from filaments obtained from brains of deceased individuals having Alzheimer's disease. The test is particularly selective and enables one to identify patients with Alzheimer's disease and distinguishes these from patient's with other neurological disorders with similar symptoms such as Parkinson's disease and Pick's disease.