发明名称 |
WATER-INSOLUBLE DERIVATIVES OF HYALURONIC ACID AND THEIR METHODS OF PREPARATION AND USE |
摘要 |
This invention describes a method for preparing water-insoluble biocompatible gels, films and sponges by reacting hyaluronic acid, or a salt thereof, with a carbodiimide in the absence of a nucleophile or a polyanionic polysaccharide. The water-insoluble gels, films and sponges of this invention may be used as surgical aids to prevent adhesions of body tissues and as drug delivery vehicles. |
申请公布号 |
WO9402517(A1) |
申请公布日期 |
1994.02.03 |
申请号 |
WO1993US07106 |
申请日期 |
1993.07.28 |
申请人 |
ANIKA RESEARCH, INC.;RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YOR |
发明人 |
KUO, JING-WEN;SWANN, DAVID, A.;PRESTWICH, GLENN, D. |
分类号 |
A61K9/00;A61K47/36;A61K47/48;A61L15/28;A61L27/20;A61L31/04;C08B37/08;(IPC1-7):C08B37/08;A61L31/00 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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