发明名称 |
4-AMINO-N &cir& _-(4-METHYL-4-PIPERIDINYL)-2-METHOXYBENZAMIDES |
摘要 |
Piperidinyl substituted benzamides of formula (I) the pharmaceutically acceptable acid addition salts thereof and the stereoisomeric forms thereof, wherein R1 is hydrogen or halo; R2 is halo; R3 is hydrogen or halo; R4 and R5 each independently are hydrogen, C1-4alkyl or haloC1-4alkyl; and the group NR4R5 may also be azido, Alk is C2-4alkanediyl; pharmaceutical compositions containing said compounds of formula (I) as active ingredient; use of said compounds as a medicine; process of preparing said compounds; compounds of formula (I) containing a radioactive isotope; process of marking 5HT2-receptor sites; and process for imaging an organ are disclosed. |
申请公布号 |
WO9402462(A1) |
申请公布日期 |
1994.02.03 |
申请号 |
WO1993EP01993 |
申请日期 |
1993.07.08 |
申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
LEYSEN, JOSEPHA, EDUARDA, MARIA, FRANCISCA;VAN DAELE, GEORGES, HENRI, PAUL |
分类号 |
G01N33/566;A61K31/445;A61K31/4468;A61K51/00;A61P25/06;A61P25/18;A61P25/22;A61P25/24;A61P43/00;C07B59/00;C07D211/58;G01N33/66;(IPC1-7):C07D211/58;G01N33/60 |
主分类号 |
G01N33/566 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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