| 发明名称 |
Vitamin D3 fluorinated analogs. |
| 摘要 |
<p>The compounds of the formula <CHEM> wherein R is hydrogen, hydroxy, or fluorine, and X is H2 or CH2 are useful as agents for the treatment of hyperproliferative disorders of the skin for the treatment of cancer and leukemia, and for the treatment of sebaceous gland diseases.</p> |
| 申请公布号 |
EP0580968(A2) |
申请公布日期 |
1994.02.02 |
| 申请号 |
EP19930107402 |
申请日期 |
1993.05.07 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BAGGIOLINI, ENRICO GIUSEPPE;SHIUEY, SHIAN-JAN;USKOKOVIC, MILAN RADOJE |
| 分类号 |
A61K8/67;A61K8/00;A61K8/58;A61K31/59;A61P17/00;A61P35/00;A61Q5/00;A61Q19/00;C07C35/52;C07C45/29;C07C49/743;C07C401/00;C07F7/18;(IPC1-7):C07C401/00 |
主分类号 |
A61K8/67 |
| 代理机构 |
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