METHOD FOR PRODUCING RECOMBINED HUMAN GP130 DERIVATIVE AND RECOMBINATION VECTOR USED THEREFOR

摘要

PURPOSE:To obtain a large amount of the purified gp130 by the use of a genetic engineering method. CONSTITUTION:The method for producing the human gp130 is characterized by culturing a host transformed with an expression vector containing a gene coding a derivative (soluble gp130) defective in the membrane-binding site of the human gp130 and subsequently collecting the derivative defective in the membrane-binding site of the human gp130 from the culture product.