发明名称 |
Preparation of purified optical isomers of desflurane |
摘要 |
A process for the preparation of highly purified optical isomers of desflurane, i.e. 2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane, is described wherein the highly purified opposite optical isomer of iso-flurane is reacted with bromine trifluoride in the cold, preferably in the presence of a solvent. A preferred solvent is bromine. The highly purified positive isomer of desflurane is advantageous over the negative isomer or the racemate. |
申请公布号 |
US5283372(A) |
申请公布日期 |
1994.02.01 |
申请号 |
US19930048091 |
申请日期 |
1993.04.15 |
申请人 |
ANAQUEST, INC. |
发明人 |
ROZOV, LEONID A.;HUANG, CHIALANG;HALPERN, DONALD F.;VERNICE, GERALD G. |
分类号 |
C07C41/22;C07C43/12;(IPC1-7):C07C41/22 |
主分类号 |
C07C41/22 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|