NUEVOS DERIVADOS DE N-ARIL Y N-HETEROARILAMIDAS Y UREA COMO INHIBIDORES DE ACIL COENZIMA A: ACIL TRANSFERASA DEL COLESTEROL (ACAT).

摘要

Compounds of the formula the pharmaceutically acceptable salts thereof, wherein Q and R<1> are as defined below, and novel carboxylic acid and acid halide intermediates used in the synthesis of such compounds. The compounds of formula I are inhibitors of acyl coenzyme A: cholesterol acyltransferase (ACAT) and are useful as hypolipidemic and antiatherosclerosis agents.