Covalent polar lipid-peptide conjugates for biological targeting

摘要

Biologically active compounds are coupled to polar lipids to provide conjugates. The conjugates have specificity for subcellular membranes by virtue of the physical and chemical properties of the lipid components. The conjugates can accumulate specifically in the desired subcellular membrane and the nature of the coupling of the biologically active compounds to the lipids is such that the compounds may be released in free form into a desired subcellular compartment.