| 摘要 |
<p>A bisheterocyclic compound represented by general formula (I), stereoisomers thereof, tautomers thereof, a pharmaceutically acceptable salt or a pharmaceutically acceptable solvate thereof, a pharmaceutical composition containing the same, and a process for the production thereof. In formula (I), R<1> and R<2> may be the same or different from each other and each represents (II) or (III), R3 represents hydrogen or a protective group, X, Y<1> and Y<2> may be the same or different from one another and each represents oxygen or sulfur, B<1> and B<2> represent each phenylene, B<3> represents phenylene, naphthylene, cyclohexylene or furo[3,2-b]furanylene, L<1> and L<2> represent each -(O)n-A-, n represents 0 or 1, and A represents a single bond or lower alkylene, provided that when n is 1, A represents alkylene and the oxygen atom of each of L<1> and L<2> is bonded to B<3>. The above compounds are useful as a hypoglycemic drug based on the activity of enhancing insulin sensitivity. <CHEM></p> |
