发明名称 |
Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis |
摘要 |
Compounds having the formula I: <IMAGE> I are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.
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申请公布号 |
US5281720(A) |
申请公布日期 |
1994.01.25 |
申请号 |
US19920966204 |
申请日期 |
1992.10.26 |
申请人 |
MERCK FROSST CANADA, INC. |
发明人 |
YOUNG, ROBERT N.;GIRARD, YVES;GILLARD, JOHN W.;TRIMBLE, LAIRD A.;SCHEIGETZ, JOHN;YERGEY, JAMES A.;DUCHARME, YVES;NICOLL-GRIFFITH, DEBORAH A.;HUTCHINSON, JOHN H. |
分类号 |
C07C65/24;C07D295/096;C07D295/24;C07D309/06;C07D309/10;C07D309/30;C07D335/02;C07D493/08;(IPC1-7):A61K31/35;C07D311/94 |
主分类号 |
C07C65/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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