发明名称 |
SUBSTITUTED STYRENE DERIVATIVES |
摘要 |
SUBSTITUTED STYRENE DERIVATIVES A b s t r a c t The new compounds of the general Formula I (wherein A stands for a C2-4 straight or branched chain alkylene group; R1 and R2 may be same or different and each stands for hydrogen, halogen, lower alkyl or lower alkoxy; or R1 and R2 together form a methylenedioxy group; R3 and R4 may be the same or different and each stands for C1-5 alkyl or C3-6 cycloalkyl or R3 and R4 together with the nitrogen atom, they are attached to, form a 4-7 membered ring which may contain as additional ring member an oxygen or sulfur atom or a further nitrogen atom and the latter nitrogen atom may optionally bear a C1-3 alkyl or benzyl substituent) and pharmaceutically acceptable acid addition salts and quaternary ammonium salts thereof possess valuable therapeutical properties and exert particularly useful tranquillant-sedative, antidepressant, antiepileptic, antiparkinson, analgesic, local anaesthetic, gastric acid secretion inhibiting and/or antianginal effect. The new compounds of the general Formula I may be prepared by methods known per se. |
申请公布号 |
CA1326484(C) |
申请公布日期 |
1994.01.25 |
申请号 |
CA19880587330 |
申请日期 |
1988.12.30 |
申请人 |
BUDAI, ZOLTAN |
发明人 |
BUDAI, ZOLTAN;PETOCZ, LUJZA;MEZEI, TIBOR;SZIRT, ENIKO NEE KISZELLY;SZECSEY, MARIA NEE HEGEDUES;GIGLER, GABOR;REITER, KLARA NEE ESESS;LAY, ARANKA NEE KONYA;FURDYGA, EVA;GYERTYAN, ISTVAN;GACSALYI, ISTVAN |
分类号 |
A61K31/15;A61K31/357;A61K31/36;A61K31/40;A61P1/04;A61P9/00;A61P25/00;A61P25/02;A61P25/04;A61P25/08;A61P25/20;A61P25/24;A61P25/26;C07C249/04;C07C249/08;C07C251/44;C07C251/58;C07D295/08;C07D295/088;C07D317/58 |
主分类号 |
A61K31/15 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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