发明名称 Use of water-soluble sucroses for the treatment and/or prevention of lesion or inflammation in the digestive tract
摘要 A method of treating and/or preventing lesion and/or inflammation of non-peptic ulcer nature in the digestive tract of an individual and a method of treating and/or preventing lesion and/or inflammation of the oesophageal, gastric and/or duodenal mucosa of an individual. The method comprises administering to a patient in need thereof a therapeutically or prophylactically effective amount of a salt or complex of a sulfated sucrose, said sucrose salt or sucrose complex being water-soluble at a neutral pH. The sulfated sucrose is at least disulfated and the salt or complex of the sucrose sulfate may be e.g. a salt or a complex with an alkali metal such as sodium or potassium, or an alkaline earth metal. An interesting sucrose sulfate is sodium sucrose octasulfate. The lesion and/or inflammation may e.g. be caused by conditions located in the oesophagus, in the stomach, in the duodenum, in the jejunem or in the ileum, colon or rectum. It may also be conditions caused by fistulae, trauma, enterotoxins, viral infections or microorganisms. Furthermore, the lesion and/or inflammation may be caused by premalignant or malignant diseases.
申请公布号 AU4312393(A) 申请公布日期 1994.01.24
申请号 AU19930043123 申请日期 1993.06.29
申请人 BUKH MEDITEC A/S 发明人 NIELS BUKH
分类号 A61K31/70;C07H11/00 主分类号 A61K31/70
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