| 摘要 |
PCT No. PCT/US93/06235 Sec. 371 Date Mar. 1, 1994 Sec. 102(e) Date Mar. 1, 1994 PCT Filed Jun. 30, 1993 PCT Pub. No. WO94/01103 PCT Pub. Date Jan. 20, 1994.A method of treating a patient suffering from a condition requiring vasodilator therapy, comprising long term, continuous adminstration of an organic nitrite to the patient in a dosage form capable of delivering a sufficient therapeutic amount of nitrite to the bloodstream of the patient thereby providing effective vasodilator therapy for at least 24 hours without the development of tolerance in the patient. The method of the invention is useful in treating conditions such as angina, particularly chronic, stable angina pectoris, ischemic diseases and congestive heart failure, and for controlling hypertension and/or impotence in male patients. |
