NMR AGENT

摘要

This invention aims at reducing a cost by avoiding the use of concentrated <17>O and to make it possible to obtain accurate data on metabolism without undergoing any change in a signal intensity due to the influences of the blood circulated later even when a large amount of an NMR agent is dosed. The NMR agent of this invention is characterized in that it contains oxygen at least in such a concentration as to be necessary for maintaining life and the content of an oxygen isotope <17>O in the oxygen is set to be less than a natural occurrence. It can be produced extremely economically by concentrating <16>O, for example, and even when a large quantity of the agent is dosed, it mixes with the blood having a high H2<17>O concentration during circulation inside the body, and the H2<17>O content in the blood as a whole does not change much. Accordingly, the circulating blood does not greatly affect the signal intensity.