COMPOSITION FOR CONTROLLED RELEASE OF AN ACTIVE SUBSTANCE AND METHOD FOR THE PREPARATION OF SUCH A COMPOSITION

摘要

Composition for delayed release of an active substance, such as a medicament, the active substance being incorporated in a polysaccharide matrix which is formed by an essentially crystalline straight-chain glucan, in particular an (alpha)-glucan which has a helix structure, such as amylodextrin or a fraction having a helix structure obtained from amylose V. The composition can contain an amount of active substance of from 0.1 to 80 % by weight and the active substance can, depending on the hydrophilicity, have a molecular weight of up to 500 or 1500 daltons. The active substance is released from the composition at a constant rate.