发明名称 OLIGOPEPTIDE DERIVATIVES AND THEIR USE IN SECONDARY CATARACT PREVENTION
摘要 <p>The invention discloses particularly compounds of formula (I) in which: X1 is a hydrogen atom, a Gly residu or an Nprotective group, and X2 is a hydroxy group, a Ser residu, a Ser-Pro or Ser-Pro-Cys group or a group of formula (II), in which R1 and R2 are independently a C1-C18 alkyl group, a C3-C8 cycloalkyl group, an aryl(C1-C4)alkyl group, and R1 may be H, or R1 et R2 together and with the nitrogen atom to which they are fixed form a pyrrolidino, piperidino or piperazinyl group optionally substituted by a C1-C4 alkyl radical or a 4-hydroxypiperidino group, or one of its addition salts with a pharmaceutical acceptable acid, used for the preparation of a secondary cataract prevention drug.</p>
申请公布号 CA2139429(A1) 申请公布日期 1994.01.20
申请号 CA19932139429 申请日期 1993.07.01
申请人 CHAUVIN LAB SA 发明人 REGNOUF DE VAINS JEAN-BERNARD;CHAMBON ODILE;BONNE CLAUDE
分类号 A61K38/00;A61F2/00;A61L27/24;A61P27/02;A61P27/12;C07K5/09;C07K14/78;(IPC1-7):C07K7/06;A61L27/00;A61K38/06;A61K38/07;A61K38/08;C07K5/08;C07K5/10 主分类号 A61K38/00
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