发明名称 |
A FUNGICIDALLY ACTIVE COMPOUND |
摘要 |
A DNA construct comprising a DNA sequence encoding an antifungal polypeptide, which sequence comprises the nucleotide sequence shown in SEQ ID No. 1 or an analogue thereof, which i) hybridizes with a DNA sequence comprising the nucleotide sequence shown in SEQ ID No. 1, or with a probe hybridizing with the nucleotide sequence SEQ ID No. 1, ii) encodes a polypeptide which reacts with an antibody reactive with at least one epitope of the polypeptide having the amino acid sequence shown in SEQ ID No. 2, and/or iii) encodes a polypeptide having the amino acid sequence shown in the appended SEQ ID No. 2 or a sequence homologous thereto, provided that the DNA sequence is different from one which encodes the polypeptide having the amino acid sequence shown in SEQ ID No. 2 except for an asparagine in position 4, an alanine in position 24, a lysine in position 32, a phenylalanine in position 42 and a tyrosine in position 50. The antifungal polypeptide encoded by the DNA construct may be used for combating or controlling fungal infections, in particular on plants. |
申请公布号 |
WO9401459(A1) |
申请公布日期 |
1994.01.20 |
申请号 |
WO1993DK00236 |
申请日期 |
1993.07.09 |
申请人 |
NOVO NORDISK A/S |
发明人 |
PEDERSEN, ANDERS HJELHOLT;HALKIER, TORBEN;NIELSEN, BIRTE, ANNETTE;LANGE, LENE;MIKKELSEN, JAN, MOELLER;RASMUSSEN, GRETHE;HANSEN, MOGENS, TRIER |
分类号 |
C12N15/09;A01N37/46;A01N63/00;A01N63/04;A61K38/00;A61P31/04;A61P31/10;C07H21/04;C07K14/37;C07K14/38;C12N1/15;C12N15/31;C12P21/02;C12R1/66;C12R1/69;(IPC1-7):C07K7/10;A61K37/02 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|