发明名称 |
Purified forms of DNASE |
摘要 |
The present invention provides the identification and characterization of two components of a recombinant preparation of DNase. These components are the purified deamidated and non-deamidated human DNases. Taught herein are the separation of these components and the use of the non-deamidated species as a pharmaceutical per se, and in particular in compositions wherein the species is disclosed within a plastic vial, for use in administering to patients suffering from pulmonary distress.
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申请公布号 |
US5279823(A) |
申请公布日期 |
1994.01.18 |
申请号 |
US19920895300 |
申请日期 |
1992.06.08 |
申请人 |
GENENTECH, INC. |
发明人 |
FRENZ, JOHN;SHIRE, STEVEN J.;SLIWKOWSKI, MARY B. |
分类号 |
C12N15/09;A61K35/74;A61K38/00;A61K38/45;A61K38/46;A61P11/00;C07K1/00;C07K1/18;C07K1/22;C07K4/12;C07K14/47;C12N9/16;C12N9/22;(IPC1-7):C12N9/22;A61K37/54 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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