发明名称 2-(2-HYDROXY-3-PHENOXYPROPYLAMINO)ETHYLPHENOXYACETAMIDES AND PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION
摘要 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamide compounds are disclosed, of general formula (I) <IMG> (I) R1 is hydrogen, fluoro or chloro, possible values of R2 include hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl and phenyl and possible values of R3 include hydrogen, alkyl, hydroxy and alkoxy, or R2 and R3 together form a methylene chain. The compounds are useful in the treatment of obesity and related conditions. Processes for their preparation are described, as are novel intermediates and pharmaceutical compositions containing them.
申请公布号 CA1326025(C) 申请公布日期 1994.01.11
申请号 CA19890588767 申请日期 1989.01.20
申请人 IMPERIAL CHEMICAL INDUSTRIES PLC 发明人 CAULKETT, PETER W. R.;COOPER, MICHAEL J.;JONES, MURDOCH A. E. G.
分类号 A61K31/165;A61K31/275;A61K31/44;A61K31/4409;A61K31/4418;A61P3/04;C07C217/30;C07C217/34;C07C231/02;C07C231/12;C07C235/18;C07C235/20;C07C237/12;C07C253/30;C07C255/60;C07C259/06;C07D213/40;C07D261/02;C07D295/18;C07D295/185;(IPC1-7):C07C237/20 主分类号 A61K31/165
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