发明名称 CHROMANDERIVATIVES AS ANGIOTENSIN II ANTAGONISTS
摘要 The invention concerns pharmaceutically useful compounds of formula (I), wherein Q is selected from (IIa), (IIb), (IIc), (IId), (IIe), (IIf), Z is carboxy or non-toxic metabolically labile ester thereof, 1HŸ -tetrazol-5-yl, -CO.NH.(1HŸ -tetrazol-5-yl) or a group of the formula -CO.NH.SO2.G1 in which G1 is alkyl, cycloalkyl or phenyl. The novel compounds are of value in treating such conditions such as hypertension and congestive heart failure. The invention further concerns processes for the manufacture of the novel compounds and the use of the compounds in medical treatment.
申请公布号 WO9400450(A1) 申请公布日期 1994.01.06
申请号 WO1993GB01294 申请日期 1993.06.18
申请人 ZENECA LIMITED 发明人 THOMAS, ANDREW, PETER
分类号 C07D311/66;C07D405/04;C07D471/04;(IPC1-7):C07D471/04;A61K31/435;C07D311/60;C07D405/06;C07D405/14 主分类号 C07D311/66
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