发明名称 SYNTHETIC PEPTIDES FOR THE TREATMENT OF MYASTHENIA GRAVIS
摘要 Peptides having at least nine amino acid residues each including an amino acid sequence which corresponds to position p200-208 or p262-266 of the human acetylcholine receptor .alpha.-subunit, but differing therefrom by one or more amino acid substitutions, are disclosed. These peptides inhibit the proliferative response of human peripheral blood lymphocytes to the myasthogenic peptides p195-212 and p259-271 and are suitable for treatment of subjects afflicted with myasthenia gravis.
申请公布号 CA2138258(A1) 申请公布日期 1994.01.06
申请号 CA19932138258 申请日期 1993.06.18
申请人 YEDA RES & DEV 发明人 SELA MICHAEL;MOZES EDNA
分类号 A61K38/00;A61K38/17;A61K39/00;A61P37/00;A61P43/00;C07K;C07K7/08;C07K14/705;(IPC1-7):C07K14/705;C07K7/06;C12Q1/68 主分类号 A61K38/00
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