| 摘要 |
A blood extracting and receiving container assembly (10) having a coating agent (22) disposed on an interior surface of a blood receiving chamber (12) and an extracting apparatus (14) to effectively isolate a blood specimen from contacting surfaces which would initiate clotting. The coating agent contains molecules which inhibit the activation of blood elements responsible for initiating blood clotting processes. A method for manipulating a blood specimen in vitro in association with the subject blood extracting and receiving assembly (10) includes the steps of coating an interior surface of the extracting and receiving container assembly (10) with nonthrombogenic coating agent (22), and, while coating agent (22) adheres to the interior surface of assembly (10), withdrawing a blood specimen (24) into the assembly. Additionally, the method includes the steps of exposing the specimen to an activating surface in a controlled manner to initiate blood clotting processes, preferably while a portion of the specimen is admixed with the nonthrombogenic agent. A clotting parameter, such as weight or clotting rate, may be correlated with a disease condition.
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